In fact, sensitive skin and other skin types, first understand the formation mechanism of sensitive skin, and then for these to find the right ingredients to solve the problem of the product. The formation mechanism of sensitive skin is the result of three points of action.
The first point: is increased immune response, which in turn leads to itching, burning sensation, erythema, capillary dilation, and other symptoms.
The second point: is impaired skin barrier function, which in turn leads to dryness, flaking, tightness, and other symptoms, affecting the epidermal microecology of the skin.
The third point: is increased sensory nerve signals, which in turn leads to burning, stinging, and itching symptoms.
For these problems, the solutions and principles are as follows.
First, for inflammation, redness, and swelling, anti-inflammatory and immune regulation are needed. For itching, histamine-like factor release inhibition is needed.
Secondly, for redness and redness, it is necessary to reduce vascular reactions and reddening.
Thirdly, for the “thin” skin barrier, it is necessary to promote the regeneration of keratin-forming cells to repair the barrier.
Fourthly, for dry, cracked, and tight skin, we need to repair the sebaceous barrier, increase the skin’s hydration capacity, which is often called “water lock”, and promote the regeneration of fibroblasts and collagen.
Fifth, in the case of tingling and itching, we need to reduce the excitability of peripheral nerve fibers and inhibit the TRPV1 pathway.
Since the formation mechanism of sensitive skin and the principle of the solution are clear, based on this, what skincare products are most suitable for sensitive skin use? Share four tricks to teach you to learn to look at the ingredients, the ingredients list contains these four things, this product will not be poor.
The first is grape seed extract, which can inhibit the NF-κB inflammatory signaling pathway, inhibit the expression of inflammatory mediators TNF-α and IL-1β, reduce the inflammatory response, destroy mast cells and hinder the release of allergy mediators.
The second is the extract of orange fruit, which is often referred to as orange peel glycosides, which, together with another ingredient, sodium heparin, can improve subcutaneous capillary blood flow, relieve capillary dilation, improve redness, promote nutrient absorption, and balance skin microcirculation.
The third ingredient is hydrolyzed collagen. It has multiple RGD (composed of arginine, glycine, and aspartate) repeats that bind to at least 8 different integrins (integral proteins). By binding to the recognition sites of integrins, it can participate in fibroblast signaling, greatly promoting fibroblast division and proliferation, enhancing the speed and number of cell differentiation, and eventually achieving the turnover process of new cells replacing old cells. It also has a large sequence of amino acid fragments that specifically recognize the tripeptide sequence in collagen’s molecular chaperone Hsp47 (heat shock protein), which is effectively firm and stable through targeted binding.
One more ingredient worth highlighting is Ginkgo biloba extract. The actual fact is that it has the ability to bind water in the skin’s stratum corneum better than glycerin and alginate, and it has a moisturizing and water-locking effect that can strengthen the skin barrier of sensitive skin.